Article
miR-20a is upregulated in serum from domestic feline with PKD1 mutation.
PloS one - 1 Jan 2022
Scalon Marcela Correa, Martins Christine Souza, Ferreira Gabriel Ginani, Schlemmer Franciele, Titze de Almeida Ricardo, Paludo Giane Regina
Abstract excerpt
Polycystic kidney disease (PKD), also known as autosomal dominant polycystic kidney disease (ADPKD) is a genetically heterogeneous condition characterized by cysts in renal parenchyma. It is the most prevalent inherited disease of domestic cats. MicroRNAs (miRNAs or ncRNA) are short, noncoding, single-stranded RNAs that may induce PKD cytogenesis by affecting numerous targets genes as well as by directly...
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