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Multi‐omics integration reveals a core network involved in host defence and hyperkeratinization in psoriasis

1 Dec 2022

Abstract excerpt

OBJECTIVES: The precise pathogenesis of psoriasis remains incompletely explored. We aimed to better understand the underlying mechanisms of psoriasis, using a systems biology approach based on transcriptomics and microbiome profiling. METHODS: We collected the skin tissue biopsies and swabs in both lesional and non-lesional skin of 13 patients with psoriasis, 15 patients with psoriatic arthritis and healthy skin...

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PMID: 36536476
DOI: 10.1002/ctm2.976

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