Article
Performance of a Commercial Multiplex Allele-Specific Polymerase Chain Reaction Kit to Genotype African-Type Glucose-6-Phosphate Dehydrogenase Deficiency.
The American journal of tropical medicine and hygiene - 1 Feb 2023
Djigo Oum Kelthoum Mamadou, Gomez Nicolas, Ould Ahmedou Salem Mohamed Salem, Basco Leonardo, Ould Mohamed Salem Boukhary Ali, Briolant Sébastien
Abstract excerpt
8-Aminoquinoline antimalarial drugs (primaquine, tafenoquine) are required for complete cure of Plasmodium vivax malaria, but they are contraindicated in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. In the absence of spectrophotometry, which is a gold standard for measuring G6PD activity, G6PD genotyping is one of the alternatives to establish a database and distribution map of G6PD enzyme...
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