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Measurement of Small Molecule Accumulation into Diderm Bacteria

19 Dec 2022

Abstract excerpt

Some of the most dangerous bacterial pathogens (Gram-negative and mycobacterial) deploy a formidable secondary membrane barrier to reduce the influx of exogenous molecules. For Gram-negative bacteria, this second exterior membrane is known as the outer membrane (OM), while for the Gram-indeterminate Mycobacteria, it is known as the “myco” membrane. Although different in composition, both the OM and mycomembrane...

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PMID: 36530146
DOI: 10.1021/acsinfecdis.2c00435

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