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Altered differentiation of endometrial mesenchymal stromal fibroblasts is associated with endometriosis susceptibility

20 Jun 2022

Abstract excerpt

Cellular development is tightly regulated as mature cells with aberrant functions may initiate pathogenic processes. The endometrium is a highly regenerative tissue, shedding and regenerating each month. Endometrial stromal fibroblasts are regenerated each cycle from mesenchymal stem cells and play a pivotal role in endometriosis, a disease characterised by endometrial cells that grow outside the uterus. Why the...

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PMID: 35725766
DOI: 10.1038/s42003-022-03541-3

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