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Zika virus as a cause of birth defects: Were the teratogenic effects of Zika virus missed for decades?

13 Dec 2022

Abstract excerpt

Zika virus (ZIKV) was identified as a teratogen in 2016 when an increase in severe microcephaly and other brain defects was observed in fetuses and newborns following outbreaks in French Polynesia (2013-2014) and Brazil (2015-2016) and among travelers to other countries experiencing outbreaks. Some have questioned why ZIKV was not recognized as a teratogen before these outbreaks: whether novel genetic changes in...

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PMID: 36513609
DOI: 10.1002/bdr2.2134

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