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Mechanism of action of paclitaxel for treating glioblastoma based on single-cell RNA sequencing data and network pharmacology

21 Nov 2022

Abstract excerpt

Paclitaxel is an herbal active ingredient used in clinical practice that shows anti-tumor effects. However, its biological activity, mechanism, and cancer cell-killing effects remain unknown. Information on the chemical gene interactions of paclitaxel was obtained from the Comparative Toxicogenomics Database, SwishTargetPrediction, Binding DB, and TargetNet databases. Gene expression data were obtained from the...

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Share to Glioma Diagnosis and Treatment
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36506527
DOI: 10.3389/fphar.2022.1076958

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