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Article

A one-year unisexual Schistosoma mansoni infection causes pathologic organ alterations and persistent non-polarized T cell-mediated inflammation in mice

24 Nov 2022

Abstract excerpt

In exhibiting gonochorism and phenotypic sexual dimorphism,Schistosomaspp. are unique among trematodes. Only females mating with male schistosomes can produce the highly immunogenic parasite eggs which determine the clinical picture of the disease schistosomiasis. The strong immune-modulatory effect of the eggs masks the influence of the adult worms. To shed light on the complexity of the immune response...

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PMID: 36505463
DOI: 10.3389/fimmu.2022.1010932

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