Article
CD34 negative HLA-DR negative acute myeloid leukaemia: A higher association with NPM1 and FLT3-ITD mutations.
International journal of laboratory hematology - 1 Apr 2023
Gajendra Smeeta, Gupta Ritu, Thakral Deepshi, Gupta Sanjeev Kumar, Jain Garima, Bakhshi Sameer, Sharma Atul, Sahoo Ranjeet Kumar, Kumar Lalit, Rai Sandeep, Singh Saroj, Upadhyay Ashish Datt
Abstract excerpt
INTRODUCTION: CD34 and HLA-DR negativity is often used as a characteristic immunophenotypic feature of acute promyelocytic leukaemia (APL) that differentiates APL from other subtypes of acute myeloid leukaemia (AML). However, other subtypes of AML, without expression of CD34 and HLA-DR antigens, have also been reported. METHODS: We analysed the HLA-DR negative de novo non-APL AML cases by dividing HLA-DR negative...
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