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Nectin-4 as Blood-Based Biomarker Enables Detection of Early Ovarian Cancer Stages

29 Nov 2022

Abstract excerpt

Ovarian cancer is the third most common gynecological malignancy and has the highest mortality rate. Owing to unspecific symptoms, ovarian cancer is not detected until an advanced stage in about two-thirds of cases. Therefore, it is crucial to establish reliable biomarkers for the early stages to improve the patients’ prognosis. The aim of this study is to investigate whether the ADAM17 substrates Nectin-4,...

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PMID: 36497350
DOI: 10.3390/cancers14235867

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