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Article

Epileptic spasms related to neuronal differentiation factor 2 (NEUROD2) mutation respond to combined vigabatrin and high dose prednisolone therapy.

BMC neurology - 9 Dec 2022

Sakpichaisakul Kullasate, Boonkrongsak Rachata, Lertbutsayanukul Punjama, Iemwimangsa Nareenart, Klumsathian Sommon, Panthan Bhakbhoom, Trachoo Objoon

Abstract excerpt

BACKGROUND: Epileptic spasms are a devastating form of early infantile epileptic encephalopathy (EIEE) with various etiologies. Early diagnosis and a shorter lead time to treatment are crucial to stop the seizures and optimize the neurodevelopmental outcome. Genetic testing has become an integral part of epilepsy care that directly guides management and family planning and discovers new targeted treatments....

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Identifiers

PMID: 36494631
DOI: 10.1186/s12883-022-02992-9
PMCID: PMC9733267

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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