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Immunity to Cryptosporidium: Lessons from Acquired and Primary Immunodeficiencies

1 Dec 2022

Abstract excerpt

Cryptosporidium is a ubiquitous protozoan parasite that infects gut epithelial cells and causes self-limited diarrhea in immunocompetent individuals. However, in immunocompromised hosts with global defects in T cell function, this infection can result in chronic, life-threatening disease. In addition, there is a subset of individuals with primary immunodeficiencies associated with increased risk for...

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PMID: 36469846
DOI: 10.4049/jimmunol.2200512

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