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Article

A Nationwide Study of Severe and Protracted Diarrhoea in Patients with Primary Immunodeficiency Diseases.

Scientific reports - 16 Jun 2017

Lee Wen-I, Chen Chien-Chang, Jaing Tang-Her, Ou Liang-Shiou, Hsueh Chuen, Huang Jing-Long

Abstract excerpt

Diarrhoea lasting longer than 14 days and failing to respond to conventional management is defined as severe and protracted diarrhoea (SD). In this study, we investigated the prevalence, pathogens and prognosis of SD in primary immunodeficiency diseases (PIDs). Among 246 patients with predominantly paediatric-onset PIDs from 2003-2015, 21 [Btk (six), IL2RG (four), WASP, CD40L, gp91 (three each), gp47, RAG2 (one...

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Source

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Identifiers

PMID: 28623282
DOI: 10.1038/s41598-017-03967-4
PMCID: PMC5473906

Genes

FOXP3
STAT1
XIAP
RAG2
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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