Article
Primary immunodeficiencies of protective immunity to primary infections.
Clinical immunology (Orlando, Fla.) - 1 May 2010
Bousfiha Aziz, Picard Capucine, Boisson-Dupuis Stéphanie, Zhang Shen-Ying, Bustamante Jacinta, Puel Anne, Jouanguy Emmanuelle, Ailal Fatima, El-Baghdadi Jamila, Abel Laurent, Casanova Jean-Laurent
Abstract excerpt
The vast majority of primary immunodeficiencies (PIDs) predispose affected individuals to recurrent or chronic infectious diseases, because they affect protective immunity to both primary and secondary or latent infections. We discuss here three recently described groups of PIDs that seem to impair immunity to primary infections without compromising immunity to secondary and latent infections. Patients with...
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