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Identification of DNA methylation signatures for hepatocellular carcinoma detection and microvascular invasion prediction

5 Dec 2022

Abstract excerpt

BACKGROUND AND AIM: Preoperative evaluation of microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC) is important for surgical strategy determination. We aimed to develop and establish a preoperative predictive model for MVI status based on DNA methylation markers. METHODS: A total of 35 HCC tissues and the matched peritumoral normal liver tissues as well as 35 corresponding HCC patients'...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36464701
DOI: 10.1186/s40001-022-00910-w

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