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Article

The LINC00152/miR-205-5p/CXCL11 axis in hepatocellular carcinoma cancer-associated fibroblasts affects cancer cell phenotypes and tumor growth.

Cellular oncology (Dordrecht, Netherlands) - 1 Dec 2022

Liu Gao, Yang Zhang-Fu, Sun Jian, Sun Bao-Ye, Zhou Pei-Yun, Zhou Cheng, Guan Ruo-Yu, Wang Zhu-Tao, Yi Yong, Qiu Shuang-Jian

Abstract excerpt

BACKGROUND: CXCL11 has been reported to be up-regulated in hepatocellular carcinoma (HCC) tissues and cancer-associated fibroblasts (CAFs), and CAF-secreted CXCL11 has been found to promote HCC cell proliferation and migration. Knowledge on how CAFs promote HCC progression is imperative for the future design of anti-tumor drugs addressing the high rates of disease recurrence. Herein, we propose a mechanism by...

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Share to Cancer-Associated Fibroblasts
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to Gene Expression Regulation, Neoplastic

Share to Liver Neoplasms

Share to Mice, Nude

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Share to RNA, Long Noncoding

Source

Open in PubMed Open full text

Identifiers

PMID: 36435866
DOI: 10.1007/s13402-022-00730-4
PMCID: PMC9747837

Genes

CXCL11
AGO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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