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Identification of Key Genes and Pathways Associated with Preeclampsia by a WGCNA and an Evolutionary Approach

17 Nov 2022

Abstract excerpt

Preeclampsia (PE) is the serious obstetric-related disease characterized by newly onset hypertension and causes damage to the kidneys, brain, liver, and more. To investigate genes with key roles in PE's pathogenesis and their contributions, we used a microarray dataset of normotensive and PE patients and conducted a weighted gene co-expression network analysis (WGCNA). Cyan and magenta modules that are highly...

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PMID: 36421809
DOI: 10.3390/genes13112134

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