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Construction and validation of a novel Ferroptosis-related gene signature predictive model in rectal Cancer

22 Nov 2022

Abstract excerpt

BACKGROUND: Rectal cancer (RC) is one of the most common malignant tumors. Ferroptosis is an iron-dependent form of cell death, which plays an important role in various cancers. However, the correlation between ferroptosis-related genes (FRGs) and prognosis in RC remains unclear. METHODS: Gene expression data from The Cancer Genome Atlas Rectum adenocarcinoma (TCGA-READ) and GSE87211 were downloaded. Clustering...

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PMID: 36414988
DOI: 10.1186/s12864-022-08996-6

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