Article
Androgen receptor polyQ alleles and COVID-19 severity in men: A replication study.
Andrology - 1 Jan 2023
López-Rodríguez Rosario, Ruiz-Hornillos Javier, Cortón Marta, Almoguera Berta, Minguez Pablo, Pérez-Tomás María Elena, Barreda-Sánchez María, Mancebo Esther, Ondo Lorena, Martínez-Ramas Andrea, Fernández-Caballero Lidia, Taracido-Fernández Juan Carlos, Herrero-González Antonio, Mahillo Ignacio, Paz-Artal Estela, Guillén-Navarro Encarna, Ayuso Carmen
Abstract excerpt
BACKGROUND: Ample evidence indicates a sex-related difference in severity of COVID-19, with less favorable outcomes observed in men. Genetic factors have been proposed as candidates to explain this difference. The polyglutamine (polyQ) polymorphism in the androgen receptor gene has been recently described as a genetic biomarker of COVID-19 severity. OBJECTIVE: To test the association between the androgen receptor...
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