Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitination

13 Nov 2022

Abstract excerpt

BACKGROUND: Cancer stem cells (CSCs) are regarded as the "seed cells" for tumorigenesis, metastasis, recurrence and drug resistance. However, specific surface markers of CSCs of different origins have not been documented. METHODS: Single-cell sequencing was used to analyze the highly expressed genes in cancer stem cells of gastric cancer patients, and it was verified that AQP5 was specifically highly expressed in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer Cells and Metastasis
Share to Hippo pathway signaling and YAP/TAZ

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36372898
DOI: 10.1186/s13046-022-02532-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AQP5 complements LGR5 to determine the fates of gastric cancer stem cells through regulating ULK1 ubiquitinationPMID 36372898Read ↗

Comparative Proteomics Analysis of Gastric Cancer Stem CellsSemantic proximity Read ↗

Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markersSemantic proximity Read ↗

SLC34A2 regulates miR‐25‐Gsk3β signaling pathway to affect tumor progression in gastric cancer stem cell‐like cellsSemantic proximity Read ↗

Curcumin suppresses LGR5(+) colorectal cancer stem cells by inducing autophagy and via repressing TFAP2A-mediated ECM pathwaySemantic proximity Read ↗

Lgr5High/DCLK1High phenotype is more common in early stage and intestinal subtypes of gastric carcinomas.Semantic proximity Read ↗

LncRNA LOXL1‐AS1 facilitates the tumorigenesis and stemness of gastric carcinoma via regulation of miR‐708‐5p/USF1 pathwaySemantic proximity Read ↗

NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cellsSemantic proximity Read ↗

Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapySemantic proximity Read ↗

ATG4A promotes tumor metastasis by inducing the epithelial-mesenchymal transition and stem-like properties in gastric cells.Semantic proximity Read ↗

Identification of BST2 as a conjunctival epithelial stem/progenitor cell markerSemantic proximity Read ↗

The regulatory role of cancer stem cell marker gene CXCR4 in the growth and metastasis of gastric cancerSemantic proximity Read ↗

OIP5-AS1/CD147/TRPM7 axis promotes gastric cancer metastasis by regulating apoptosis related PI3K-Akt signalingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.