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Developmental validation of STRmix™ NGS, a probabilistic genotyping tool for the interpretation of autosomal STRs from forensic profiles generated using NGS.

Forensic science international. Genetics - 1 Jan 2023

Cheng Kevin, Bright Jo-Anne, Kelly Hannah, Liu Yao-Yuan, Lin Meng-Han, Kruijver Maarten, Taylor Duncan, Buckleton John

Abstract excerpt

We describe the developmental validation of the probabilistic genotyping software - STRmix™ NGS - developed for the interpretation of forensic DNA profiles containing autosomal STRs generated using next generation sequencing (NGS) also known as massively parallel sequencing (MPS) technologies. Developmental validation was carried out in accordance with the Scientific Working Group on DNA Analysis Methods (SWGDAM)...

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PMID: 36370677
DOI: 10.1016/j.fsigen.2022.102804

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