Article
Genetic and Functional Effects of Adiponectin in Type 2 Diabetes Mellitus Development.
International journal of molecular sciences - 4 Nov 2022
Tang Yu-Hui, Wang Yeh-Han, Chen Chin-Chang, Chan Chia-Jung, Tsai Fuu-Jen, Chen Shih-Yin
Abstract excerpt
Diabetes mellitus (DM) is a common chronic metabolic disease, and the C57BLKsJ-db/db mice are good animal models for type 2 diabetes mellitus (T2DM). In this study, Western blotting and immunohistochemistry (IHC) were employed to examine the protein expression of adiponectin in the liver tissues of T2DM mice with different disease courses (4, 16, and 32 weeks). Adiponectin expression reduced in the liver tissues...
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