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Article

Effects of rifampicin, CYP2B6 and ABCB1 polymorphisms on efavirenz plasma concentration in Chinese patients living with HIV and tuberculosis.

International journal of STD & AIDS - 1 Jan 2023

Zhang Li, Meng Xianmin, Dong Ping, Qi Tangkai, Liu Li, Wang Bin

Abstract excerpt

BACKGROUND: Tuberculosis (TB) is the leading opportunistic infection of people living with human immunodeficiency virus (HIV; PLWH). Cytochrome P450 (CYP) 2B6 and ATP-binding cassette sub-family B member 1 (ABCB1) are involved in the metabolism and transportation of efavirenz. The study was aimed to investigate the effects of rifampicin, CYP2B6 and ABCB1 polymorphisms on efavirenz exposure in Chinese PLWH...

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Identifiers

PMID: 36356965
DOI: 10.1177/09564624221134137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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