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Comparison of the performance of two targeted metagenomic virus capture probe-based methods using reference control materials and clinical samples

17 May 2024

Abstract excerpt

Viral enrichment by probe hybridization has been reported to significantly increase the sensitivity of viral metagenomics. This study compares the analytical performance of two targeted metagenomic virus capture probe-based methods: (i) SeqCap EZ HyperCap by Roche (ViroCap) and (ii) Twist Comprehensive Viral Research Panel workflow, for diagnostic use. Sensitivity, specificity, and limit of detection were...

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PMID: 38757981
DOI: 10.1128/jcm.00345-24

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