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The expression changes of transcription factors including ANKZF1, LEF1, CASZ1, and ATOH1 as a predictor of survival rate in colorectal cancer: a large-scale analysis

7 Nov 2022

Abstract excerpt

INTRODUCTION: Transcription factors (TFs) are essential for many biological processes and regulate the expression of several genes. This study's objective was to analyze the abnormalities in TF expression, their impact on patient prognosis, and related pathways in colorectal cancer (CRC). METHOD: The expression alterations of all TFs were investigated using the cancer genome atlas and GSE39582 data. Clinical data...

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PMID: 36344988
DOI: 10.1186/s12935-022-02751-3

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