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Article

Stepwise molecular mechanisms responsible for chemoresistance in bladder cancer cells

7 Nov 2022

Abstract excerpt

Chemotherapy resistance is an obstacle to cancer therapy and is considered a major cause of recurrence. Thus, understanding the mechanisms of chemoresistance is critical to improving the prognosis of patients. Here, we have established a stepwise gemcitabine-resistant T24 bladder cancer cell line to understand the molecular mechanisms of chemoresistance within cancer cells. The characteristics of the stepwise...

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PMID: 36344487
DOI: 10.1038/s41420-022-01242-8

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