Article
Gene drive by Fusarium SKC1 is dependent on its competing allele.
Fungal genetics and biology : FG & B - 1 Nov 2022
Lohmar Jessica M, Rhoades Nicholas A, Hammond Thomas M, Brown Daren W
Abstract excerpt
The Fusarium verticillioides SKC1 gene driver is transmitted to offspring in a biased manner through spore killing. The mechanism that allows SKC1 to kill non-SKC1 offspring while sparing others is poorly understood. Here we report that gene drive by SKC1 is dependent on SKC1's competing allele. We propose that SKC1's competing allele influences the ability of a genome defense process to detect SKC1, and we...
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