Article
Lower expression of the equine maternally imprinted gene IGF2R is related to the slow proliferation of hinny embryonic fibroblast in vitro.
Molecular biology reports - 1 Jan 2023
Wang Xisheng, Asgenbaatar Nairag, Shen Yingchao, Yi Minna, Zhao Bilig, Ren Hong, Davshilt Toli, Ulaangerel Tseweendolmaa, Wang Min, Burenbaatar Als, Tian Shuyue, Li Bei, Dugarjav Manglai, Bou Gerelchimeg
Abstract excerpt
BACKGROUND: Proliferation of embryonic fibroblasts under the same cell culture conditions, hinny embryonic fibroblasts (HiEFs) was slower than horse embryonic fibroblast (HEFs), donkey embryonic fibroblasts (DEFs) and mule embryonic fibroblasts (MuEFs). The imprinted genes IGF2 and IGF2R are important for cell proliferation. Therefore, we investigated whether the slower proliferation of HiEFs is related to an...
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