Article
[MEN for multiple endocrin neoplasms: When evokate MEN? Update 2022].
La Revue de medecine interne - 1 Jan 2023
Duval M, Haissaguerre M
Abstract excerpt
Multiple endocrine neoplasia (MEN) are genetic predisposition syndromes to endocrine tumors including MEN1, MEN2 and exceptionally MEN4. MEN are transmitted in an autosomal dominant fashion with a high penetrance. Classically, there is no genotype/phenotype correlation for NEM1 whereas this is the case for NEM2. Patients with NEM1, linked to an inactivating mutation of the menin gene, may present with: primary...
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