Article
Asciminib in chronic myeloid leukemia.
Drugs of today (Barcelona, Spain : 1998) - 1 Oct 2022
Assanto Giovanni Manfredi, Scalzulli Emilia, Breccia Massimo
Abstract excerpt
Despite the fact that, in the last years, life expectancy of chronic myeloid leukemia (CML) patients has reached that of the normal population, a significant proportion of CML patients is likely to fail treatment with first- or second-generation tyrosine kinase inhibitors (TKIs). Failure to first-line treatment is commonly due to molecular resistance or unbearable toxicity. New specific compounds are tested in...
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