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Matrix Gla protein (MGP), GATA3, and TRPS1: a novel diagnostic panel to determine breast origin

25 Oct 2022

Abstract excerpt

BACKGROUND: Metastatic breast carcinoma is commonly considered during differential diagnosis when metastatic disease is detected in females. In addition to the tumor morphology and documented clinical history, sensitive and specific immunohistochemical (IHC) markers such as GCDFP-15, mammaglobin, and GATA3 are helpful for determining breast origin. However, these markers are reported to show lower sensitivity in...

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PMID: 36284362
DOI: 10.1186/s13058-022-01569-1

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