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Article

Mutagenic, Acute, and Subchronic Toxicity Studies of the Hesperetin-7-Glucoside-β-Cyclodextrin Inclusion Complex.

International journal of toxicology - 1 Jan 2000

Moriwaki Masamitsu, Kito Kento, Nakagawa Ryo, Tominaga Etsuko, Kapoor Mahendra P, Matsumiya Yoshiki, Fukuhara Tomohisa, Yamagata Hiroshi, Katsumata Toyohisa, Minegawa Kazuyuki

Abstract excerpt

Hesperetin glucosides such as hesperidin and hesperetin-7-glucoside are abundantly present in citrus fruits and have various pharmacological properties. However, the potential toxicity of hesperetin glucosides remains unclear. An initial assessment of the safety of hesperetin-7-glucoside-β-cyclodextrin inclusion complex (HPTGCD) as a functional food ingredient was undertaken to assess toxicity and mutagenic...

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PMID: 36280476
DOI: 10.1177/10915818221134022
PMCID: PMC9841476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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