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Profiling of cell‐free DNA methylation and histone signatures in pediatric NAFLD: A pilot study

20 Oct 2022

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in children and adolescents, increasing the risk of its progression toward nonalcoholic steatohepatitis (NASH), cirrhosis, and cancer. There is an urgent need for noninvasive early diagnostic and prognostic tools such as epigenetic marks (epimarks), which would replace liver biopsy in the future. We used plasma samples from...

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PMID: 36264206
DOI: 10.1002/hep4.2082

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