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DNA binding, antitubercular, antibacterial and anticancer studies of newly designed piano-stool ruthenium( ii ) complexes

1 Jan 2022

Abstract excerpt

) values for the antitubercular activity of Ru-1 and Ru-2 were 4.87 ± 1.32 μM and 5.78 ± 0.54 μM, respectively. A cytotoxic study of these complexes was performed against the human breast cancer cell line (MCF-7) and the human embryonic kidney cell line (HEK293) (normal cells). The study revealed meaningful activity of the Ru-1 complex against (cancer) MCF-7 cells, while the viability of HEK293 (normal) cells in...

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PMID: 36250384
DOI: 10.1039/d2dt02577a

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