Article
Cancer: Can CRISPR Become a Game Changer?
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP - 1 Oct 2022
Khan Sikandar Hayat
Abstract excerpt
Recent development in CRISPR technologies has emerged as a powerful tool for genome editing, which can become a powerful diagnostic and therapeutic option for cancer patients. While literature search demonstrates some successes in this dimension in animal models and phase-I human trials, still the promised panacea has shortcomings in terms of off-target mutations (OTMs), minimal efficiency, and tailoring...
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