Article
Liquid biopsy for detecting epidermal growth factor receptor mutation among patients with non-small cell lung cancer treated with afatinib: a multicenter prospective study.
BMC cancer - 4 Oct 2022
Fujii Hiroaki, Nagakura Hideyuki, Kobayashi Nobuaki, Kubo Sousuke, Tanaka Katsushi, Watanabe Keisuke, Horita Nobuyuki, Hara Yu, Nishikawa Masanori, Miura Kenji, Koizumi Harumi, Ito Yu, Tsubakihara Motofumi, Miyazawa Naoki, Kudo Makoto, Shinkai Masaharu, Kaneko Takeshi
Abstract excerpt
BACKGROUND: This study aimed to determine the effectiveness of liquid biopsy in detecting epidermal growth factor receptor (EGFR) mutations at diagnosis, disease progression, and intermediate stages. METHODS: This prospective, multicenter, observational study included 30 patients with non-small cell lung cancer treated with afatinib, harboring a major EGFR mutation confirmed by tumor tissue biopsy. We collected...
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