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Article

Relative frequency of cytomegalovirus UL56 gene mutations detected in genotypic letermovir resistance testing.

Antiviral research - 1 Nov 2022

Chou Sunwen, Kleiboeker Steven

Abstract excerpt

Genotypic testing for letermovir (LMV) resistance was performed by Sanger sequencing of cytomegalovirus terminase gene UL56 (codons 202-412) in 1165 diagnostic specimens, disclosing 36 sequence variants among 173 (14.8%) of the specimens, including one or more LMV resistance mutations in 134 specimens. Codon 325 mutations (C325Y/F/W/R) were the most common (108 specimens), followed by those at codon 369...

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Identifiers

PMID: 36170912
DOI: 10.1016/j.antiviral.2022.105422
PMCID: PMC9759347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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