Article
Multiple primary sporadic gastrointestinal stromal tumors in the adult: an underestimated entity.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2008
Gasparotto Daniela, Rossi Sabrina, Bearzi Italo, Doglioni Claudio, Marzotto Alessandra, Hornick Jason L, Grizzo Alessandra, Sartor Chiara, Mandolesi Alessandra, Sciot Raf, Debiec-Rychter Maria, Dei Tos Angelo Paolo, Maestro Roberta
Abstract excerpt
PURPOSE: Gastrointestinal stromal tumors (GIST) are commonly regarded as solitary tumors. The occurrence of multiple lesions is considered an extraordinary event restricted to pediatric GISTs and rare hereditary conditions. Beyond these well-defined situations, the presentation of multiple synchronous lesions is commonly viewed as the result of the metastatic spreading of a single primary GIST. Based on this...
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