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Pathogenicity of Avian Polyomaviruses and Prospect of Vaccine Development

19 Sept 2022

Abstract excerpt

Polyomaviruses are nonenveloped icosahedral viruses with a double-stranded circular DNA containing approximately 5000 bp and 5–6 open reading frames. In contrast to mammalian polyomaviruses (MPVs), avian polyomaviruses (APVs) exhibit high lethality and multipathogenicity, causing severe infections in birds without oncogenicity. APVs are classified into 10 major species: Adélie penguin polyomavirus, budgerigar...

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PMID: 36146885
DOI: 10.3390/v14092079

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