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Article

CYP450 core involvement in multiple resistance strains of Aedes aegypti from French Guiana highlighted by proteomics, molecular and biochemical studies.

PloS one - 1 Jan 2021

Epelboin Yanouk, Wang Lanjiao, Giai Gianetto Quentin, Choumet Valérie, Gaborit Pascal, Issaly Jean, Guidez Amandine, Douché Thibaut, Chaze Thibault, Matondo Mariette, Dusfour Isabelle

Abstract excerpt

Insecticide resistance is a worldwide threat for vector control around the world, and Aedes aegypti, the main vector of several arboviruses, is a particular concern. To better understand the mechanisms of resistance, four isofemale strains originally from French Guiana were isolated and analysed using combined approaches. The activity of detoxification enzymes involved in insecticide resistance was assayed, and...

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PMID: 33428654
DOI: 10.1371/journal.pone.0243992
PMCID: PMC7799788

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