Article
Homozygous CADPS2 Mutations Cause Neurodegenerative Disease with Lewy Body-like Pathology in Parrots.
Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2022
Lorenzo-Betancor Oswaldo, Galosi Livio, Bonfili Laura, Eleuteri Anna Maria, Cecarini Valentina, Verin Ranieri, Dini Fabrizio, Attili Anna-Rita, Berardi Sara, Biagini Lucia, Robino Patrizia, Stella Maria Cristina, Yearout Dora, Dorschner Michael O, Tsuang Debby W, Rossi Giacomo, Zabetian Cyrus P
Abstract excerpt
BACKGROUND: Several genetic models that recapitulate neurodegenerative features of Parkinson's disease (PD) exist, which have been largely based on genes discovered in monogenic PD families. However, spontaneous genetic mutations have not been linked to the pathological hallmarks of PD in non-human vertebrates. OBJECTIVE: To describe the genetic and pathological findings of three Yellow-crowned parrot (Amazona...
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