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Article

Upregulation of KIF18B facilitates malignant phenotype of esophageal squamous cell carcinoma by activating CDCA8/mTORC1 pathway.

Journal of clinical laboratory analysis - 1 Oct 2022

Xie Jiangliu, Wang Bo, Luo Wenjie, Li Chen, Jia Xunchao

Abstract excerpt

BACKGROUND: Kinesin family member 18B (KIF18B) has been regarded as an oncogene that is abnormally overexpressed in some cancers, but its mechanism in esophageal squamous cell carcinoma (ESCC) remains unclear, which is thereby investigated in this study. METHODS: Bioinformatics analysis was performed to analyze the expression of KIF18B in esophageal carcinoma (ESCA). Quantitative real-time polymerase chain...

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Identifiers

PMID: 36085568
DOI: 10.1002/jcla.24633
PMCID: PMC9550975

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