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Oncogenic and Stemness Signatures of the High-Risk HCMV Strains in Breast Cancer Progression

1 Sept 2022

Abstract excerpt

BACKGROUND: Human cytomegalovirus (HCMV) oncomodulation, molecular mechanisms, and ability to support polyploid giant cancer cells (PGCCs) generation might underscore its contribution to oncogenesis, especially breast cancers. The heterogeneity of strains can be linked to distinct properties influencing the virus-transforming potential, cancer types induced, and patient's clinical outcomes. METHODS:...

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PMID: 36077806
DOI: 10.3390/cancers14174271

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