Article
Determining the origin of different variants associated with familial mediterranean fever by machine-learning.
Scientific reports - 8 Sept 2022
Adato Orit, Brenner Ronen, Levy Avi, Shinar Yael, Shemer Asaf, Dvir Shalem, Ben-Zvi Ilan, Livneh Avi, Unger Ron, Kivity Shaye
Abstract excerpt
A growing number of familial Mediterranean fever (FMF) patients in Israel do not have a single country of origin for all four grandparents. We aimed to predict the Mediterranean fever gene (MEFV) variant most likely to be found for an individual FMF patient, by a machine learning approach. This study was conducted at the Sheba Medical Center, a referral center for FMF in Israel. All Jewish referrals included in...
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