Article
Targeting SDF ‐1 as an efficient strategy to resolve skin hyperpigmentation issues with Himanthalia elongata extract
5 Sept 2022
Abstract excerpt
BACKGROUND: During aging, human skin is facing hyperpigmentation disorders: senile lentigo (chronobiologic aging) leads to loss of melanogenesis' control while solar lentigo (UV exposure) promotes an increase of oxidized proteins, melanogenesis, and lipofuscin. AIMS: Stromal-cell-derived-factor-1 (SDF-1) was identified as key regulator of hyperpigmentation and its expression is reduced in senescent fibroblasts,...
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