Article
Skin senescence: mechanisms and impact on whole-body aging.
Trends in molecular medicine - 1 Feb 2022
Franco Ana Catarina, Aveleira Célia, Cavadas Cláudia
Abstract excerpt
The skin is the largest organ and has a key protective role. Similar to any other tissue, the skin is influenced not only by intrinsic/chronological aging, but also by extrinsic aging, triggered by environmental factors that contribute to accelerating the skin aging process. Aged skin shows structural, cellular, and molecular changes and accumulation of senescent cells. These senescent cells can induce or...
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