Article
Predicting COVID-19 disease severity from SARS-CoV-2 spike protein sequence by mixed effects machine learning.
Computers in biology and medicine - 1 Oct 2022
Sokhansanj Bahrad A, Rosen Gail L
Abstract excerpt
Epidemiological studies show that COVID-19 variants-of-concern, like Delta and Omicron, pose different risks for severe disease, but they typically lack sequence-level information for the virus. Studies which do obtain viral genome sequences are generally limited in time, location, and population scope. Retrospective meta-analyses require time-consuming data extraction from heterogeneous formats and are limited...
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