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Article

Using Machine Learning for Predicting the Effect of Mutations in the Initiation Codon.

IEEE journal of biomedical and health informatics - 1 Nov 2022

Castell-Diaz J, Abad-Navarro F, de la Morena-Barrio M E, Corral J, Fernandez-Breis J T

Abstract excerpt

The effect of mutations has been traditionally predicted by studying what may happen due to the substitution of one amino acid for another one. This approach may be effective for mutations with impact in the function of the protein, but ineffective for mutations in the translation initiation codon. Such mutation might avoid the generation of the protein. Consequently, specific methods for predicting the effect of...

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PMID: 35998169
DOI: 10.1109/JBHI.2022.3200966

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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