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Identification of key genes for hypertrophic cardiomyopathy using integrated network analysis of differential lncRNA and gene expression

4 Aug 2022

Abstract excerpt

Objective: Hypertrophic cardiomyopathy (HCM) is a complex heterogeneous heart disease. Recent reports found that long non-coding RNAs (lncRNAs) play an important role in the progression of cardiovascular diseases. The present study aimed to identify the novel lncRNAs and messenger RNAs (mRNAs) and determine the key pathways involved in HCM. Methods: The lncRNA and mRNA sequencing datasets of GSE68316 and...

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PMID: 35990977
DOI: 10.3389/fcvm.2022.946229

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