Point-of-care HIV viral load and targeted drug resistance mutation testing versus standard care for Kenyan children on antiretroviral therapy (Opt4Kids): an open-label, randomised controlled trial.

doi:10.1016/S2352-4642(22)00191-2

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Point-of-care HIV viral load and targeted drug resistance mutation testing versus standard care for Kenyan children on antiretroviral therapy (Opt4Kids): an open-label, randomised controlled trial.

The Lancet. Child & adolescent health - 1 Oct 2022

Patel Rena C, Oyaro Patrick, Thomas Katherine K, Wagude James, Mukui Irene, Brown Evelyn, Hassan Shukri A, Kinywa Eunice, Oluoch Frederick, Odhiambo Francesca, Oyaro Boaz, Kingwara Leonard, Karauki Enericah, Yongo Nashon, Otieno Lindah, John-Stewart Grace C, Abuogi Lisa L

Abstract excerpt

BACKGROUND: Feasible, scalable, and cost-effective approaches to ensure virological suppression among children living with HIV are urgently needed. The aim of the Opt4Kids study was to determine the effect of point of care viral load and targeted drug resistance mutation testing in improving virological suppression among children on antiretroviral therapy (ART) in Kenya. METHODS: In this open-label, individually...

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PMID: 35987208
DOI: 10.1016/S2352-4642(22)00191-2
PMCID: PMC9482947

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